Biology Contact Us Artificial Intelligence Biotechnology Computer Science Cybersecurity Data Analytics and Visualization Digital Marketing and Media Mathematics Occupational Therapy Physician Assistant Physics Speech-Language Pathology The Department of Biology at Stern College for Women offers a broad liberal arts education, providing ¾Ã¾ÃÈÈ with an understanding of the biotic world, from molecules and cells through organisms and ecosystems. A wide range of courses cover the fundamentals of modern biology, as well as cutting-edge areas of molecular biology and biomedical research.Faculty have on-campus research laboratories and involve the undergraduates in their projects. Faculty members publish their research in scientific peer-reviewed journals, frequently listing their undergraduate research interns as co-authors. The quality of science training at Stern College for Women has made our ¾Ã¾ÃÈÈ highly competitive for external summer undergraduate research internships in industry, universities and medical institutions.Course work and research opportunities develop ¾Ã¾ÃÈÈ' analytical and experimental skills, enabling them to continue their study of science at advanced levels of graduate and professional education. Students majoring in biology pursue careers in medicine, dentistry and optometry, as well as in a spectrum of other health-related professions, including physical therapy, occupational therapy, nursing, physician assistant, nutrition and genetic counseling.Other ¾Ã¾ÃÈÈ continue their graduate education in public health, biotechnology and basic and applied biomedical research.For an overview of recent student accomplishments in STEM, click here (PDF).For an annual publication detailing our student and departmental accomplishments in STEM, please view our journal, .For further information, please contact Dr. Alyssa Schuck, schuck@yu.eduMission StatementThe mission of the Department of Biology is for undergraduates majoring in biology to be prepared and to be qualified to pursue advanced studies in the biomedical sciences as related to human health care and/or to pursue employment in various biology-related fields. These milestones will be achieved by providing courses covering a spectrum of sub-disciplines with biology, so as to provide majors in biology with a comprehensive background in the principles of modern biology, with hands-on skills in the usage of laboratory instrumentation, with an understanding of scientific literature and of research methodologies, and with proficiencies in written and oral communication.Program Student Learning GoalsBiology majors will be able to understand the main principles of modern biology, with an emphasis on the biomedical sciences.Biology majors will be able to apply skills in modern laboratory techniques and knowledge of the scientific method to analyze scientific problems and to create their own scientific investigations.Biology majors will be able to critically evaluate scientific literature according to established scientific criteria.Biology majors will be able to express scientific ideas, both in written and oral communication.Derech HatevaDerech HaTeva, a Journal of Torah and Science is a publication of the undergraduate ¾Ã¾ÃÈÈ of Stern College for Women that synthesizes Torah and scientific knowledge and thus represents the unique intellectual strengths and talents of our ¾Ã¾ÃÈÈ. This journal is cataloged in the National Library of Congress. Derech HaTeva is distributed nationally and internationally and has received much praise. You can download a copy at the . YU Journal of Medicine and DentistryIn the Spring semester, 2022, undergraduates at Stern College and Yeshiva College initiated a new publication, The ¾Ã¾ÃÈÈ Journal of Medicine and Science. According to their "Mission Statement," the journal was created "for the student body and faculty of ¾Ã¾ÃÈÈ, as well as for the broader communities with which the university is associated and for the world at large." Articles can be found at the. Program Information Courses Please see the Schedule of Classes for the current semester’s offerings. Biology (BIOL)1006 Human Genetics 3 creditsAn introduction to human genetics. Topics include inheritance patterns of single gene and multi gene traits, the genetic basis of disease and behavior, the development of DNA technology and its application to law and medicine. This course is for non-science majors and does not count toward the Biology major.1060 Biology and Public Health 3 creditsThe goal of this course is to educate ¾Ã¾ÃÈÈ on the convergence of Biology and Public Health. Students will engage with diseases whose impact on the individual impacts society and diseases where societal norms and standards influence understanding and progression. We will discuss our current methods for assessing and understanding the burden of disease on our society. Recent experiences with Covid-19 and public health will be used as a springboard to discuss many of the intersections of public health and biology and a segue into other important topics of public health including, but not limited to, vaccines, obesity, diabetes, mental health, AIDS. Understanding biology and public health necessitates the understanding of certain biological concepts as well as the understanding that while ‘the science’ can inform decisions, public health requires that we also understand the impacted populations, recognizing that different communities may behave differently, and public health needs to adapt to as many people within a given society. Special attention will be paid to the disparity in public health issues and responses in various local and global communities. Also offered as SCIE 1060 or PUB 1060. Not for Bio major/minor1011&1013, 1012&1014 Principles of Biology I and II 4 creditsFor majors. Introductory analysis of the various biological concepts at the molecular, cellular, and organismal levels. First semester: biochemistry of molecules, enzyme kinetics, cellular anatomy and physiology, cellular energetics and metabolism, cellular signaling; second semester: cellular reproduction, genetics, molecular biology, population biology, evolution, and comparative human physiology. Laboratory work, including dissections, complements the lectures. (lecture: 3 hours; lab: 3 hours)1376 Biochemistry 3 creditsStructure and function of biomolecules; kinetics and mechanism of enzymes; bioenergetics and metabolism; membrane structure and dynamics; signal transduction. Prerequisite: CHEM 1213C or permission of the instructor.2105 Basic Immunology 2 creditsBasic principles, theories, and current problems in immunology. Emphasis on the development, functions and interplay of the various immune cells in health and disease, with particular attention to transplantation, vaccination, allergy, and autoimmunity. Prerequisites: BIOL 1012.2601 Human Development 2 creditsFocus on normal human embryonic and fetal development, as well as on congenital anomalies and birth defects. Fetal physiology and maternal-fetal interactions are presented, as well as other related topics, such as assisted reproductive technology. Prerequisite: BIOL 10122730 Human Anatomy 4 creditsA regional approach to the study of the human body, with special focus on human locomotory anatomy. Laboratory emphasizes mammalian (cat) dissection. (lecture: 3 hours; lab: 4 hours). Laboratory fee. Prerequisite or co-requisite: BIOL 1012.3207 Cell Biology 4 creditsBasic architecture of cellular organelles and components; dynamics of growth, nutrition, cell cycle, metabolism, and metabolic regulation; specialized cell functions. Laboratory accompanies lectures. (lecture: 3 hours; lab: 3 hours) Laboratory fee. Prerequisite: BIOL 1012C. Prerequisite or co-requisite: CHEM 1046.3221 Nutrition 3 creditsClinical nutrition, directed to common medical disorders, relevant physiology, nutrition¬al implications, and therapy. Nutrition in gastrointestinal disorders, diabetes, cancer, and AIDS are discussed. This course does not count toward the Biology major. 3241 Pharmacology 2 creditsMajor aspects of pharmacology: pharmacokinetics, pharmacodynamics, mechanisms of action, physiologic effects, as well as adverse effects of drugs. Course is organ¬ized by drug class according to either organ system or therapeutic category. Prerequisite: BIOL 10123513 Genetics 4 creditsCourse spans Mendelian genetics, chromosomal morphology, cell divisions, linkage, gene mapping, DNA replication, chromosome morphology, gene mutation, chromosomal aberrations, gene regulation, extranuclear genetics, behavioral genetics, epigenetics, and basic principles of biotechnology. Laboratory exercises complement lectures. (lecture: 3 hours; lab: 3 hours) Laboratory fee. Prerequisite: BIOL 1012C.3521 Molecular Biology 4 creditsA comprehensive study of the gene in prokaryotic and eukaryotic systems. Analysis of the molecular structure of DNA and the chromosome, RNA structure and transcription, RNA processing, translation into proteins, structure and organization of the genes and their regulatory regions, protein-DNA interactions, gene expression mechanisms. (lecture: 3 hours; lab: 3 hours) Laboratory fee. Prerequisite: BIOL 1012.3728 Human Physiology 4 creditsPhysicochemical principles involved in life processes. Lectures and laboratory illustrate these principles in the physiological systems of humans. (lecture: 3 hours; lab: 3 hours) Laboratory fee. Prerequisite: BIOL 1012.3730 Reproductive Biology 2 creditsThe course focuses on different aspects of human reproduction and reproductive health. Topics include spermatogenesis, oogenesis, menstrual cycle, fertile window and fertilization, breastfeeding, breast and ovarian disorders, infertility, assisted reproductive techniques (e. g. in vitro fertilization). Prerequisite: BIOL 1012C.3735 Biology of Women’s Health 2 creditsBiology of conditions affecting women’s health. Topics covered include reproduction, cardiovascular disease, osteoporosis, cancer, and autoimmune diseases. Articles from medical journals and clinical trial data are discussed. Prerequisite: BIOL 1012.3750 Medical Biochemistry 3 creditsReviews major human metabolic pathways with focus on biochemical alterations that accompany a wide range of human diseases and conditions. Emphasis on advanced methods of molecular medicine for diagnosis and treatment of genetic and metabolic disorders. Prerequisite: BIOL 1012C; Pre- or co-requisite: CHEM 1213C.3780 Biology of Cancer 3 creditsUnderstand the history of cancer research and the underlying mechanisms that contribute to the development and the progression of cancer as well as the ways in which we use these mechanisms to treat cancer. Prerequisite: BIOL 1012; Pre or Co-requisite: BIOL 3207 3830 Neurobiology 2-3 creditsNerve cells and their organization into complex nervous systems; major concepts in neurobiology, including impulse conduction, synaptic transmission, sensory processing, motor function, and memory.Prerequisite: BIOL 10124023 Microbiology 4 creditsTopics include prokaryotic cell structure and function, microbial nutrition, growth and control, microbial metabolism, bacteriophages, and microbial genetics. Laboratory exercises complement lectures. (lecture: 3 hours; lab: 3 hours) Laboratory fee. Prerequisite: BIOL 1012.Pre- or co-requisite: CHEM 1010 or 1045.4901, 4902, 4903, 4904 Independent StudySee Academic Information and Policies section. Laboratory fee on an individual basis.4930- 4936 Current Topics in Biology 1-3 creditsSelected subjects from current developments in a variety of biological disciplines, such as kinesiology, public health, immunology and disease, medical genetics, environmental issues. 1-credit Journal Clubs are graded on a P/F basis.Prerequisites: BIOL 1012 and permission of the instructor.4947, 4948 Research Internship - Credits depend on number of hours devotedResearch project at an approved laboratory in New York under the joint guidance of the head of the laboratory and a faculty member at Stern College for Women. Prerequisites: BIOL 1012C and permission of the instructor. Requirements Biology MajorThe Biology major offers three tracks: the General track; the Molecular and Cellular track; and the Neuroscience track. All three tracks require BIOL 1011, 1012 (lecture), 1013, 1014 (laboratory); CHEM 1045, 1046 (lecture) and CHEM 1047 (laboratory); two courses chosen from MATH 1410 or 1412, MATH 1413, STAT 1021, and COMP 1001 or 1300.Organic Chemistry, Biochemistry/Medical Biochemistry, and Physics are strongly recommended.The additional specific requirements for each track follow:General Track: 20-22 BIOL credits: 3207 or 3521 and 3513 or 4203, plus two additional 4-credit lecture/laboratory courses and either an additional 4-credit lecture/laboratory course, or two lecture-only courses. Biochemistry may count toward the required biology credits. Molecular and Cellular Track: 24 BIOL credits including four 4-credit lecture/lab courses with the following distribution: 3207, 3513, 3521. The remaining 12 credits may be selected from: 2105, 2601, 3241, 3730, 3750, 3780, 4023, CHEM 1376, and CHEM 1377.Neuroscience Track: 15-16 BIOL credits and 19 PSYC credits: BIOL 3830, plus 12-13 BIOL credits chosen from 3207, 3241, 3513, 3728, and either 3750 or 1376. PSYC 1010, 2100, 2150, 3804, 3810, and 3815. Some of the Psychology courses may also apply toward the General Education Requirements. See the Departmental Fact Sheet for details.Biology MinorBIOL 1011 and 1012 (lecture), 1013 and 1014 (laboratory) and 10-11 additional BIOL credits, at least 8 of which must be in advanced lecture/laboratory courses. Biochemistry may count toward the biology minor.View major/minor fact sheets at the Academic Advisement Center webpage. Faculty Anya AlayevClinical Professor of Biology Harvey BabichProfessor of Biology Karen BaconProfessor of Biology The Mordecai D. Katz and Dr. Monique C. Katz Dean of ¾Ã¾ÃÈÈ Faculty of Arts and SciencesBill BassmanAdjunct Instructor of BiologyJohn GolinAdjunct Professor of BiologyAmanda KatzClinical Assistant Professor of BiologyBrenda LoewyClinical Associate Professor of Biology Director, Pre-health advisementJeffrey MollinSenior Laboratory Instructional Specialist in Biology Director, Pre-nursing, Pre-OT, Pre-PT, and Pre-PAJennifer OdienAdjunct Instructor of BiologyTatyana Kievsky Laboratory Instructional Specialist in BiologyAlyssa SchuckClinical Professor of Biology Margarita VigodnerProfessor of BiologyDoris and Ira Kukin Chair in BiologyRaizy WeinrebAdjunct Instructor of Biology Richard WeissClinical Associate Professor of Biology Faculty Achievements Faculty Grants (only current grants are listed) Dr. Margarita VigodnerNIH Rl5. "Sumoylation and its regulation in testicular Sertoli cells," 2023-2026, $450,000.Chelst, Schreiber and Zwas Book Grant, $1,500 towards student research.A recipient of the 2023-2024 Faculty Research Fund award through the YU Office of the Provost.Katz School Faculty Research Award, academic year 2023-2024. Dr. Anya AlayevOngoing research support: NIH Grant Number 1 R15 CA220021-01 Research area: Targeting Estrogen Related Receptor alpha in triple negative breast cancer Involves many undergraduate research interns Faculty Awards (academic year, 2023-2024)Dr. Harvey Babich2024 Dean Karen Bacon Faculty AwardDr. Alyssa Schuck2024 Senior Class Award for General StudiesDr. Margarita Vigodner 2023-2024 Faculty Research Fund Award Faculty Publications (2013-2023, only) Applebaum, N., Chemel, S., Matveev, S., Pal, S.S., Sengupta, A., Lucas, B., and Vigodner, M., 2023, Phosphoproteome analysis of the crosstalk between sumoylation and phosphorylation in mouse spermatocytes. Biochem. Biophys. Res. Commun. 681:194-199.Musheyev, D., Miller, E., Birnbaum, N., Miller, E., Erblich, S., Schuck, A., and Alayev, A., 2022, Inhibition of ERK signaling for treat1nent of ERRa positive TNBC, PLOS One 3 :480-496.Alhumaidi, M., Nentwig, L.M., Rahman, H., Schmitt, L., Rudrow, A., Harris, A., Dillon, C., Retrepo, L., Lamping, E., Arya, N·., Ambudkar, S.V., Choy, J.S., and Golin, J., 2022, Residues forming the gating regions of symmetric multidrug transporter Pdr5 also play roles in conformationalswitching and protein folding, J.Biol. Chem., 298(12): 102689 [Correction: 2023, 299(4): 104666.]Banerjee, A., Rahman, H., Prasad, R., and Golin, J., 2022, How fungal multidrug transporters mediate hyper-resistance through DNA amplification and mutation, Mol. Microbiol., 118(1-2):3- 15.Musheyev, D. and Alayev, A., 2022, Endocrine therapy resistance: what we know and future directions, Explor. Target Antitumor Ther., 3 :480-496.Vigodner, M., Lucas, B., Kemeny, S., Schwartz, T., and Levy, R. 2020, Identification of sumoylated targets in proliferating mouse spermatogonia and human testicular seminomas. Asian J. Urol., Mar 27.[Epub ahead of print]. Cuesta, R., Berman, A.Y., Alayev, A., and Holz MK., 2019, Estrogen receptor α promotes protein synthesis by fine-tuning the expression of the eukaryotic translation initiation factor 3 subunit f (eIF3f). J Biol Chem. 294::2267-2278. Schafler. E.D., Thomas, P.A., Ha, S., Wang, Y., Bermudez-Hernandez, K., Tang, Z., Fenyö. D., Vigodner, M., and Logan, S.K., 2018, UXT is required for spermatogenesis in mice pubmed.ncbi.nlm.nih.gov/29649254 PLoS One. 13::e0195747.Bostner, J., Alayev, A., Berman, A.Y., Fornander, T., Nordenskjöld, B., Holz, M.K. and StÃ¥l, O. 2018, Raptor localization and estrogen-dependent breast cancer growth. Breast Cancer Res. Treat. 168:17-27. Alayev, A., Salamon, R.S., Schwartz, N.S., Berman, A.Y., Wiener, S.L., Holz, and M.K., 2017, Combination of rapamycin and resveratrol for treatment of bladder cancer. J. Cell Physiol. 232:436-446. Xiao, Y., Lucas, B., Molcho, E., and Vigodner, M., 2017, Cross-talk between sumolyation and phosphorylation in mouse spermatocytes, Biochem. Biophys. Res. Comm. 487:640-645. Alayev, A., Salamon, R.S., Schwartz, N.S, Berman, A.Y., Wiener, S.L., and Holz, M.K., 2017, Combination of rapamycin and resveratrol for treatment of bladder cancer. J. Cell Physiol., 232:436-446. Xiao, Y., Pollack, D., Andrusier, M., Levy, A., Callaway, M., Nieves, E., and Vigodner M., 2016, Identification of cell specific targets of sumoylation during mouse spermatogenesis, Reproduction, 151:149-166. Alayev, A., Salamon, R.S., Berger, S.M., Schwartz, N.S., Cuesta, R., Snyder, R.B., Holz, M.K., 2016, mTORC1 directly phosphorylates and activates ERRα upon estrogen stimulation, Oncogene 35:3535-3543. Alayev, A., Salamon, R.S., Manna, S., Schwartz, N.S., Berman, A.Y., and Holz, M.K., 2016, Estrogen induces RAD51C expression and localization to sites of DNA damage. Cell Cycle 15:3230-3239. Alayev, A., Salamon, R.S., Sun, Y., Schwartz, N.S, Yu, J.J, and Holz, M.K., 2015, The combination of rapamycin and resveratrol causes apoptosis and reduces .growth of TSC2-deficient xenograft tumors, Am. J. Respir. Cell Mol. Biol., Apr 6 [Epub ahead of print]. Alayev, A., Doubleday, P.F., Berger, S.M., Ballif, B.A., and Holz, M.K., 2014, Phosphoproteomics reveals resveratrol-dependent inhibition of Akt/mTORC1/S6K1 signaling, J. Proteome  Res. 13:5734-5742. Xiao, Y., Pollack, D., Nieves, E., Winchell, A., Callaway, M., and Vigodner, M., 2015, Can your protein be sumoylated? A quick summary and important tips to study SUMO- modified proteins. Anal. Biochem., 77:95-97.Alayev, A., Sun, Y., Snyder, R.B., Berger, S.M., Yu, L.J., and Holz, M.K., 2014, Resveratrol prevents rapamycin-induced upregulation of autophagy and selectively induces apoptosis in TSC-2 deficient cells, Cell Cycle, 13: 371-382.Shrivastava, V., Marmor, H., Chernyak, S., Goldstein, M., Feliciano, M., and Vigodner, M., 2014, Cigarette smoke affects posttranslational modifications and inhibits capacitation-induced changes in human sperm proteins, Reprod. Toxicol. 43:125-129. Vigodner, M., Shrivastava, V., Gutstein, L.E., Schneider, J., Nieves, E., Goldstein, M., Feliciano, M., and Callaway, M., 2013, Localization and identification of sumoylated proteins in human sperm; excessive sumoylation as a marker of defective spermatozoa, Human Reprod. 28: 210-223. Schuck, A.G., Weisburg, J.H., Greenbaum, R.E., Golfeiz, M.D., Segal, J.R., Weiss, R.A., Liebman, E.C., Zuckerbraun, H.L., Babich, H., 2013, Selective cytotoxicity of a grape seed proanthocyanidin extract to human oral carcinoma HSC-2 cells, Cell Develop. Biol. 2:121-128. Schuck, A.G., Weisburg, J.H., Esan, H., Robin, E.F., Bersson, A.R., Weitschner, J.R., Lahasky, T., Zuckerbraun, H.L., and Babich, H., 2013, Cytotoxic and proapoptotic activities of gallic acid, an inducer of oxidative stress, to human oral cancer HSC-2 cells, Oxid. Antioxid. Med. Sci. 2:225-229. Weisburg, J.H., Schuck, A.G., Reiss, S.E., Wolf, B.J., Fertel, S.R., Zuckerbraun, H.L. and Babich., H., 2013, Ellagic acid: A dietary polyphenol, selectively cytotoxic to HSC-2 oral carcinoma cells, Anticancer Res. 33:1829-1836. Torah U’Mada Publications (2022-2023, only):Weiss, R., 2023, "Kriat Yam-Suf: In G-d and people we trust," National Council of Young Israel/Pesach Torah Journal, 2(3)45-47,Babich, H, 2023, The science behind some Mishnaic and Talmudic passages, 27:55-65.Weiss. R., 2022, Passover Seder priorities for health care professionals, National Council of Young Israel/Pesach Torah Journal, 3 42-45.Babich, 1-I., 2022, Adom HaRishon and his contemporaries-soulless humanoids, 26:47-52.Torah U'Mada Presentations: (2022-2023, only):Weiss, R., 2023, Ethical dilemmas in transplant medicine., Panel Discussion/Israel Bonds-NJ HealthProfessionals/Chabad SE Morris County, March 16.Weiss, R., 2023, Infertility: Halachic approaches, Health Education for Students Society/SCW (HESS),February 22.Weiss, R., 2022, Ethical and halachic risks associated with harvesting organs, YI/Talmud Torah ofFlatbush, December 3.Weiss, R., 2022, Embryo selection, Olami's Jewish Health Club/NYU, Hunter College, November 8. Research Opportunities On-campus research opportunities in the laboratories of Dr. Vigodner, Dr. Alayev and Dr. Schuck Bar Ilan University - YU Summer ¾Ã¾ÃÈÈ Research Internship